Scientific Foundations & Citations

ALIGNMETRIX provides informational insights only. It is not a medical device and does not provide medical advice, diagnosis, or treatment. Decisions regarding medical care should be made in consultation with a qualified healthcare professional.

ALIGNMETRIX is grounded in established research across cognitive science, stress physiology, emotional regulation, executive functioning, self-regulation, relational health, and psychological well-being. These domains represent widely accepted scientific frameworks that inform the constructs reflected in ALIGNMETRIX insights.

ALIGNMETRIX applies a proprietary integrative model to synthesize these constructs. This document provides scientific context only and does not disclose scoring methodology.

• Sweller, J. (1988). Cognitive load during problem solving: Effects on learning. Cognitive Science, 12(2), 257–285. https://doi.org/10.1207/s15516709cog1202_4
• Maslach, C., & Leiter, M. P. (2016). Understanding the burnout experience: Recent research and its implications for psychiatry. World Psychiatry, 15(2), 103–111. https://doi.org/10.1002/wps.20311
• World Health Organization. (2019, May 28). Burn-out an occupational phenomenon: International Classification of Diseases. https://www.who.int/news/item/28-05-2019-burn-out-an-occupational-phenomenon-international-classification-of-diseases
• McEwen, B. S. (2017). Neurobiological and systemic effects of chronic stress. Chronic Stress, 1, 2470547017692328. https://doi.org/10.1177/2470547017692328
• Diamond, A. (2013). Executive functions. Annual Review of Psychology, 64, 135–168. https://doi.org/10.1146/annurev-psych-113011-143750
• Baumeister, R. F., & Vohs, K. D. (2016). Strength model of self-regulation as a limited resource: Assessment and prospects. Advances in Experimental Social Psychology, 54, 67–127. https://doi.org/10.1016/bs.aesp.2016.04.001
• Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352
• DeVellis, R. F., & Thorpe, C. T. (2022). Scale development: Theory and applications (5th ed.). SAGE.
• Cronbach, L. J. (1951). Coefficient alpha and the internal structure of tests. Psychometrika, 16(3), 297–334. https://doi.org/10.1007/BF02310555